School of Pharmacy, Hangzhou Normal University, Hangzhou 311121, China. Key Laboratory of Element Class Anti-Cancer Chinese Medicines, Engineering Laboratory of Development and Application of Traditional Chinese Medicines, Collaborative Innovation Center of Traditional Chinese Medicines of Zhejiang Province, Hangzhou Normal University, Hangzhou 311121, China. College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China. School of Traditional Chinese Medicine, Guangdong Pharmaceutical University, Guangzhou 510006, China.